Cognition
Dihexa
Also known as: N-Hexanoic-Tyr-Ile-(6)-aminohexanoic amide, PMI-6
A small peptide derivative from angiotensin IV research. Dihexa is considered one of the most potent cognition-related peptides in preclinical neurology research.
Structure
- Molecular formula
- C₂₇H₄₄N₄O₅
- Molecular weight
- 508.7 Da
- Amino acids
- 2 (modifiziertes Dipeptid)
Mechanism of action
Dihexa binds hepatocyte growth factor (HGF) and potentiates HGF/c-Met signalling, which promotes synapse formation and dendritic branching in preclinical models.
Studies
More in Cognition
More detail (research areas, comparisons, FAQ): German lexicon entry.