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Metabolism & incretins

Acetyl GLP-1/GIP

Also known as: Acetyliertes Inkretin-Dualpeptid, GLP-1/GIP-Hybridpeptid

An acetylated dual peptide with structural elements of GLP-1 and GIP. It activates the GLP-1 and GIP receptors at the same time and serves as a research tool for combined incretin pharmacology.

Structure

Sequence
Acetyl-GLP-1(7-36)-GIP(1-30) Hybridsequenz
Molecular formula
C₂₂₀H₃₄₁N₅₇O₆₅
Molecular weight
~4800 Da
Amino acids
36

Mechanism of action

Dual GLP-1R/GIPR agonist that stimulates cAMP signalling in beta cells and fat cells.

More in Metabolism & incretins

More detail (research areas, comparisons, FAQ): German lexicon entry.