Skin & copper peptides
MT-2
Also known as: Melanotan II, Melanotan 2
A cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), known for its melanogenic effect and studied in pigmentation research.
Structure
- Sequence
- Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH₂
- Molecular formula
- C₅₀H₆₉N₁₅O₉
- Molecular weight
- 1,025 Da
- Amino acids
- 7
- Half-life
- ~2–3 hours
Mechanism of action
MT-2 activates the MC1 receptor in melanocytes and stimulates melanin production. It also activates other melanocortin receptor subtypes (MC3R, MC4R) in the brain, which affects appetite and sexual function.
Studies
More in Skin & copper peptides
More detail (research areas, comparisons, FAQ): German lexicon entry.