Regeneration
MGF
Also known as: Mechano Growth Factor, IGF-1Ec, PEG-MGF
A splice variant of the IGF-1 gene expressed in muscle under mechanical load. MGF activates satellite stem cells and initiates muscle repair.
Structure
- Molecular formula
- C₁₂₁H₂₀₀N₄₂O₃₉S₂
- Molecular weight
- 2,867 Da
- Amino acids
- 24
- Half-life
- ~5–7 minutes (unmodifiziert) / ~mehrere days (PEG-MGF)
Mechanism of action
MGF is expressed in response to mechanical load and acts locally on satellite cells, promoting their proliferation while delaying differentiation.
Studies
More in Regeneration
More detail (research areas, comparisons, FAQ): German lexicon entry.